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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX16
All Species:
17.88
Human Site:
S378
Identified Species:
30.26
UniProt:
O60231
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60231
NP_003578.2
1041
119264
S378
L
Q
G
D
E
E
P
S
A
P
P
T
S
T
Q
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
S381
L
Q
G
N
E
E
P
S
A
P
P
T
S
T
Q
Rhesus Macaque
Macaca mulatta
NP_001098636
1044
119602
S381
L
Q
G
D
E
E
P
S
A
P
P
T
S
T
Q
Dog
Lupus familis
XP_538827
1042
119346
S379
L
Q
G
N
E
E
P
S
G
P
S
P
P
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
A2A4P0
1244
142553
F472
L
V
E
E
E
P
P
F
L
R
G
H
T
K
Q
Rat
Rattus norvegicus
NP_997661
1044
119245
S380
L
Q
G
D
E
E
P
S
S
G
P
P
L
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZI74
1231
137685
N368
S
L
G
L
V
D
K
N
N
N
P
L
S
H
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956318
1054
121479
S391
G
T
L
S
E
K
E
S
E
P
E
L
S
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609946
894
102815
G302
T
K
D
K
K
M
I
G
C
T
Q
P
R
R
V
Honey Bee
Apis mellifera
XP_001122325
831
95330
T239
D
N
K
I
I
G
C
T
Q
P
R
R
V
A
A
Nematode Worm
Caenorhab. elegans
O45244
1008
114272
E347
G
T
N
E
E
V
V
E
T
E
A
E
K
K
K
Sea Urchin
Strong. purpuratus
O17438
455
51461
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
P463
L
N
R
P
W
E
D
P
M
P
E
T
G
E
R
Baker's Yeast
Sacchar. cerevisiae
P24384
1145
129992
M462
T
E
W
E
K
N
R
M
N
E
S
I
S
Y
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.4
97.2
N.A.
39.5
95.9
N.A.
N.A.
24.7
N.A.
72.7
N.A.
57
53.9
55.8
24.5
Protein Similarity:
100
99.7
99.5
98.8
N.A.
57.7
97.8
N.A.
N.A.
41.3
N.A.
85.6
N.A.
71.7
66.4
75.2
33.1
P-Site Identity:
100
93.3
100
60
N.A.
26.6
60
N.A.
N.A.
20
N.A.
26.6
N.A.
0
6.6
6.6
0
P-Site Similarity:
100
100
100
73.3
N.A.
40
73.3
N.A.
N.A.
33.3
N.A.
33.3
N.A.
13.3
13.3
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
40
36.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.5
57.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
22
0
8
0
0
8
29
% A
% Cys:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% C
% Asp:
8
0
8
22
0
8
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
8
22
58
43
8
8
8
15
15
8
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
15
0
43
0
0
8
0
8
8
8
8
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% H
% Ile:
0
0
0
8
8
0
8
0
0
0
0
8
0
0
0
% I
% Lys:
0
8
8
8
15
8
8
0
0
0
0
0
8
15
8
% K
% Leu:
50
8
8
8
0
0
0
0
8
0
0
15
8
0
0
% L
% Met:
0
0
0
0
0
8
0
8
8
0
0
0
0
0
0
% M
% Asn:
0
15
8
15
0
8
0
8
15
8
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
8
43
8
0
50
36
22
8
0
0
% P
% Gln:
0
36
0
0
0
0
0
0
8
0
8
0
0
8
36
% Q
% Arg:
0
0
8
0
0
0
8
0
0
8
8
8
8
8
8
% R
% Ser:
8
0
0
8
0
0
0
43
8
0
15
0
43
15
0
% S
% Thr:
15
15
0
0
0
0
0
8
8
8
0
29
8
22
0
% T
% Val:
0
8
0
0
8
8
8
0
0
0
0
0
8
0
8
% V
% Trp:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _